CASE REPORT
Pulmonary granular cell tumor coexisting with interstitial lung disease – a rare case report
1
Department of Pathology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey
2
Department of Pathology, Bingol State Hospital, Bingol, Turkey
3
Department of Pathology, Kanuni Training and Research Hospital, Trabzon, Turkey
4
Department of Chest Diseases, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey
5
Department of Chest Diseases, Ahi Evren Chest Cardiovascular Surgery Training and Research Hospital, Trabzon, Turkey
Submission date: 2025-01-16
Final revision date: 2025-08-26
Acceptance date: 2025-09-25
Publication date: 2026-01-19
Pol J Pathol 2025;76(4):338-342
KEYWORDS
TOPICS
ABSTRACT
A granular cell tumor (GCT) is a soft tissue neoplasm of rare occurrence in the lung. A 44-year-old male asphalt worker had interstitial lung disease. Incidentally, a 7 mm polypoid nodule was observed at the entrance of the right upper lobe bronchus. Tumor cells were characterized by a large granular eosinophilic cytoplasm and small, uniform nuclei. The neoplastic cells were diffuse positive for S-100, CD-68, NSE, vimentin, and SOX-10, and focal positive for calretinin and inhibin A. This case is unique in its distinction as the second literature case of pulmonary GCT coexisting with interstitial lung disease.
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| eISSN: | 2084-9869 |
| ISSN: | 1233-9687 |
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