CASE REPORT
Synovial sarcoma of the stomach: case report and systematic review of the literature
1
Department of Tumor Pathology, Maria Sklodowska-Curie National Research Institute of Oncology, Krakow Branch, Poland
2
Department of Pathology Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland
3
Department of Surgical Oncology, Specialist Hospital, Podkarpacki Oncology Center in Brzozow, Poland
4
Department of Radiology and Imaging Sciences, Specialist Hospital, Podkarpacki Oncology Center in Brzozow, Poland
Publication date: 2020-07-22
Pol J Pathol 2020;71(2):181-193
KEYWORDS
ABSTRACT
Synovial sarcoma is a rare mesenchymal malignant neoplasm that presents a specific t(X;18) translocation forming SS18(SYT)-SSX chimera gene. It is most commonly seen in soft tissues of the extremities. The digestive tract is an exceptional site of involvement. We report a case of primary gastric synovial sarcoma in a 48-year-old female. Differential diagnosis of synovial sarcoma from other spindle cell, mesenchymal and cytokeratin-positive tumors is critical for the treatment and prognosis. Immunohistochemistry studies and molecular analysis are required to settle a proper diagnosis.
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