CASE REPORT
Atypical spindle cell lipomatous tumour presenting as a large retroperitoneal mass – a case report and review of the literature
1
Department of Pathology, University Hospital of the Canary Islands, University of La Laguna, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain
2
Department of General and Digestive Surgery, University Hospital of the Canary Islands, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain
Submission date: 2022-09-20
Final revision date: 2022-12-01
Acceptance date: 2022-12-07
Publication date: 2023-03-12
Corresponding author
Martyna Aleksandra Krupinska
Martyna Aleksandra Krupinska, MD Department of Pathology University Hospital of the Canary Islands Ofra, s/n. La Cuesta 38320 San Cristóbal de La Laguna Santa Cruz de Tenerife, Spai
Martyna Aleksandra Krupinska, MD Department of Pathology University Hospital of the Canary Islands Ofra, s/n. La Cuesta 38320 San Cristóbal de La Laguna Santa Cruz de Tenerife, Spai
Pol J Pathol 2022;73(4):364-370
KEYWORDS
TOPICS
ABSTRACT
Atypical spindle cell lipomatous tumour (ASCLT) is a benign neoplasm that presents a variable proportion of atypical spindle and adipocytic cells, frequently expressing CD34, and embedded in myxoid or collagenous matrix. An important feature is a constant lack of either MDM2 or CDK4 amplification. It typically arises in the extremities. The retroperitoneum is a rare site of involvement. We report a case of a retroperitoneal ASCLT in a 62-year-old male. A differential diagnosis of ASCLT from the other mesenchymal, spindle-cell, and lipomatous tumours is crucial for optimal treatment and significantly influences the prognosis. A diagnosis should be warranted by the immunohistochemistry and molecular findings.
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| eISSN: | 2084-9869 |
| ISSN: | 1233-9687 |
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