CASE REPORT
The rare combination of low-grade thyroid-like nasopharyngeal papillary adenocarcinoma and squamous cell carcinoma: a case report and literature review
1
Department of Pathology, Cukurova University Faculty of Medicine, Adana, Turkey
2
Department of Pathology, Van Training and Research Hospital, Van, Turkey
3
Department of Pathology, Adana City Training and Research Hospital, Adana, Turkey
4
Department of Ear, Nose, Throat Diseases, Adana City Training and Research Hospital, Adana, Turkey
Submission date: 2022-07-31
Acceptance date: 2022-12-07
Publication date: 2023-03-07
Corresponding author
Tugba Toyran
Tugba Toyran Department of Pathology Cukurova University Faculty of Medicine Adana, Turkey
Tugba Toyran Department of Pathology Cukurova University Faculty of Medicine Adana, Turkey
Pol J Pathol 2022;73(4):359-363
KEYWORDS
TOPICS
ABSTRACT
Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma (TL-LGNPA) is an extremely rare neoplasm that generally originates from the nasopharynx surface epithelium. The case presented herein is of a 70-year-old male patient referred from another centre, who was observed to have this tumour together with squamous cell carcinoma. The clinicopathological findings of this combination are presented, which has very rarely been mentioned in the literature.
Although the prognosis of TL-LGNPA is generally excellent, it may sometimes be combined with other tumours, and therefore it must be kept in mind that it could have a clinically more aggressive course.
Although the prognosis of TL-LGNPA is generally excellent, it may sometimes be combined with other tumours, and therefore it must be kept in mind that it could have a clinically more aggressive course.
REFERENCES (27)
1.
Li M, Wei J, Yao X, et al. Clinicopathological features of low-grade thyroid-like nasopharyngeal papillary adenocar- cinoma. Cancer Res Treat 2017; 49: 213.
2.
Wenig BM, Hyams VJ, Heffner DK. Nasopharyngeal papil- lary adenocarcinoma. A clinicopathologic study of a low-grade carcinoma. Am J Surg Pathol 1988; 12: 946-953.
3.
Zhang WL, Ma S, Havrilla L, et al. Primary thyroid-like low- grade nasopharyngeal papillary adenocarcinoma: a case report and literature review. Medicine (Baltimore) 2017; 96: e8851.
4.
Horino T, Ichii O, Hamada-Ode K, et al. Thyroid-like low- grade nasopharyngeal papillary adenocarcinoma: a case report. Mol Clin Oncol 2016; 5: 693-696.
5.
Oide T, Kadosono O, Matsushima J, et al. Thyroid-like low- grade nasopharyngeal papillary adenocarcinoma with squa- mous differentiation: a novel histological finding. Hum Pathol 2017; 70: 43-48.
6.
Thompson L. World Health Organization classification of tumours: pathology and genetics of head and neck tumours. Ear Nose Throat J 2006; 85: 74.
7.
Carrizo F, Luna MA. Thyroid transcription factor-1 expression in thyroid-like nasopharyngeal papillary adenocarcinoma: report of 2 cases. Ann Diagn Pathol 2005; 9: 189-192.
8.
Wu PY, Huang CC, Chen HK, et al. Adult thyroid-like low- grade nasopharyngeal papillary adenocarcinoma with thyroid transcription factor-1 expression. Otolaryngol Head Neck Surg 2007; 137:837-838.
9.
Fu CH, Chang KP, Ueng SH, et al. Primary thyroid-like papillary adenocarcinoma of the nasopharynx. Auris Nasus Larynx 2008; 35: 579-582.
10.
Bansal A, Pradeep KE, Gumparthy KP. An unusual case of low-grade tubulopapillary adenocarcinoma of the sinonasal tract. World J Surg Oncol 2008; 6: 54.
11.
Ohe C, Sakaida N, Tadokoro C, et al. Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: report of two cases. Pathol Int 2010; 60: 107-111.
12.
Sillings CN, Weathers DR, Delgaudio JM. Thyroid-like papillary adenocarcinoma of the nasopharynx: a case report in a 19-year-old male. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 110: e25.
13.
Petersson F, Pang B, Loke D, et al. Biphasic low-grade nasopharyngeal papillary adenocarcinoma with a prominent spindle cell component: report of a case localized to the posterior nasal septum. Head Neck Pathol 2011; 5: 306-313.
14.
Huang CH, Chang YL, Wang CP, et al. Positive immunostaining of thyroid transcription factor-1 in primary nasopharyngeal papillary adenocarcinoma. J Formos Med Assoc 2015; 114: 473-474.
15.
Ozer S, Kayahan B, Cabbarzade C, et al. Thyroid-like papillary adenocarcinoma of the nasopharynx with focal thyroglobulin expression. Pathology 2013; 45: 622-624.
16.
Oishi N, Kondo T, Nakazawa T, et al. Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: case report and literature review. Pathol Res Pract 2014; 210: 1142-1145.
17.
Ozturk K, Midilli R, Veral A, et al. Primary thyroid-like papillary adenocarcinoma of the nasal septum: a case report. Ear Nose Throat J 2015; 94: E19-21.
18.
Wu R, Liu H. Clinicopathological features of low-grade nasopharyngeal papillary adenocarcinoma. Zhonghua Bing Li Xue Za Zhi 2014; 43: 613-617.
19.
Zhang X, Xu X, Qian K, et al. Low-grade thyroid-like papillary of the nasopharynx with squamous differentiation: report of a case. Lin Chuang Yu Shi Yan Bing Li Xue Za Zhi 2015; 31: 1199-1200.
20.
Kang Z, Ou Y, Yao L, et al. Low-grade nasopharyngeal papillary adenocarcinoma: report of two cases and literature review.Lin Chuang Yu Shi Yan Bing Li Xue Za Zhi 2015; 31: 1165-1167.
21.
Li JF, Ye Q, Hong B, et al. Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: report of a case. Zhonghua Bing Li Xue Za Zhi 2011; 40: 638-639.
22.
Han S, Yang F, Yuan C, et al. Clinicopathological observation of 1 cases of low grade nasopharyngeal papillary adenocarcinoma. Lin Chuang Yu Shi Yan Bing Li Xue Za Zhi 2013; 29: 328-330.
23.
Chen Z, Zhuo M, Zheng X. Thyroid-like low-grade nasopharyngeal papillar adenocarcinoma: one case report. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2014; 28: 1266-1267.
24.
Ordonez NG. Value of thyroid transcription factor-1 immunostaining in tumor diagnosis: a review and update. Appl Immunohistochem Mol Morphol 2012; 20: 429-444.
25.
Imamura Y. CD15 (C3D-1) immunoreactivity in normal, benign and malignant thyroid lesions. Appl Immunohistochem 1998; 6: 181-186.
26.
Ortiz-Rey JA, Alvarez C, San Miguel P, et al. Expression of CDX2, cytokeratins 7 and 20 in sinonasal intestinal-type adenocarcinoma. Appl Immunohistochem Mol Morphol 2005; 13: 142-146.
27.
Wang CP, Chang YL, Chen CT, et al. Photodynamic therapy with topical 5-aminolevulinic acid as a post-operative adjuvant therapy for an incompletely resected primary nasopharyngeal papillary adenocarcinoma: a case report. Lasers Surg Med 2006; 38: 435-438.
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