CASE REPORT
Langerhans cell sarcoma: a case report and review of the literature
Submission date: 2015-10-26
Final revision date: 2016-04-23
Acceptance date: 2016-04-24
Publication date: 2016-08-02
Pol J Pathol 2016;67(2):172-178
KEYWORDS
TOPICS
ABSTRACT
We present the case of a 62-year-old male patient with a three-month history of pain in the left shoulder. Magnetic resonance imaging of the left scapula showed an osteo-destructive lesion. H&E stained sections revealed a Langerhans cell sarcoma, and immunohistochemistry was performed additionally; CD68, CD163, CD14, fascin, HLA-DR, lysozyme, S100 CD1a and langerin showed a positive reaction, while CD20, CD30, CD34, CD31, pan-cytokeratin, AE/1AE3, SMA, desmin, EMA, ERG, INI-1, CD21, CD4, PLAP, MPO and CD117c were negative. We suggested palliative treatment with chemotherapy and radiation. The patient refused any treatment and died 2 weeks later.
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