CASE REPORT
Microinvasive lobular carcinoma arising in a benign phyllodes tumour – a short report and brief review of the literature
 
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St. George’s Hospital, London, United Kingdom
 
 
Submission date: 2023-05-14
 
 
Acceptance date: 2024-06-05
 
 
Publication date: 2024-08-08
 
 
Corresponding author
Zoltan Szollosi
Zoltan Szollosi St. George’s Hospital London, United Kingdom
 
 
Pol J Pathol 2024;75(3):249-251
 
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ABSTRACT
Lobular carcinoma in situ (LCIS) with microinvasion is a rare entity which is rarely reported in the literature. We describe a case of microinvasive LCIS following excision of a fibroepithelial lesion. The lesion was graded as U3 and M3 on ultrasonography and mammography respectively, and on core needle biopsy was described as a fibroepithelial lesion with ‘unusual features’. Microscopic examination revealed a fibroepithelial lesion focally colonised by florid E-cadherin negative LCIS with multiple foci of microinvasive classical lobular carcinoma, which lacked a myoepithelial layer on CK5 and S100 staining.
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eISSN:2084-9869
ISSN:1233-9687
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