CASE REPORT
Sebaceous vs. lipid-rich carcinoma of the breast. Clinicopathological characteristics and correlations – a report of two cases and a literature review
1
Department of Pathology, Faculty of Medicine Niš, University of Niš, Serbia
2
Department of Oncology, Faculty of Medicine Niš, University of Niš, Serbia
3
Department of Microbiology and Immunology, Faculty of Medicine Niš, University of Niš, Serbia
4
Department of Surgery, Faculty of Medicine Niš, University of Niš, Serbia
5
Department of Pathology, Faculty of Medicine Foča, University of East Sarajevo, Republic of Srpska, Bosnia and Herzegovina
Submission date: 2024-02-27
Final revision date: 2024-06-20
Acceptance date: 2024-07-10
Publication date: 2024-09-20
Corresponding author
Nikola Živković
Prof. Nikola Živković Department of Pathology Faculty of Medicine Niš University of Niš Blvd. Dr Zorana Djindjića 81 18000 Niš, Serbia
Prof. Nikola Živković Department of Pathology Faculty of Medicine Niš University of Niš Blvd. Dr Zorana Djindjića 81 18000 Niš, Serbia
Pol J Pathol 2024;75(3):241-248
KEYWORDS
TOPICS
ABSTRACT
Primary sebaceous and lipid-rich carcinomas are extremely rare. Sebaceous carcinoma cells are large and oval with light, partially vacuolated cytoplasm. The second population consists of cells located mainly on the peripheral parts of tumour beaches. Those cells are of smaller calibre and are fusiform in appearance. Lipid- rich carcinoma is made up of multiple cell populations. The predominant cell type is with a distinctly light, vacuolated, and partially optically clear cytoplasm. Pathohistological analysis may be overlapping. On one side there is a tumour with a relatively excellent prognosis, and on the other, a highly aggressive carcinoma with a tendency for early metastases.
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